Karatas Okyay, E., Guven Santur, S., Ozsahin, Z., Karakayali Ay, C. · Menopause · 2026
Three-arm sham-controlled RCT (n=105): four weekly EFT sessions cut menopausal symptoms 46% (MRS 18.66 to 10.14; d=1.01 vs sham) and depressive symptoms 45% (Meno-D 13.97 to 7.69; d=0.87 vs sham), while sham-point tapping with identical psychological components was indistinguishable from no treatment on symptoms (p=1.000) and flat on depression. Quality of life improved in both tapping arms vs control (EFT vs sham not significant). Hot-flash (vasomotor) and sexual domains were unchanged in all arms.
Menopause sits squarely in the 45-65 audience, and this trial gives three usable, defensible claims at once: symptom reduction, depression reduction, and a large sleep-complaint improvement - each against a blinded structural sham, not just a waitlist. It is also the strongest single answer to the placebo objection: identical ritual on fake points did nothing for symptoms or depression. Do not claim hot-flash relief; that domain was null.
Replication with longer follow-up, intention-to-treat handling, objective or clinician-rated outcomes, and a clinically depressed menopausal sample; a direct comparison against CBT or mindfulness for menopausal symptoms, as the authors themselves recommend.
| Design | Randomized trial |
|---|---|
| Participants | 105 people |
| Population | Postmenopausal women aged 45-59 (natural menopause >=1 year, no hormone therapy, not selected for symptom severity), two family health centers in Malatya, Turkiye, Dec 2023-Jun 2024; three-arm parallel RCT (block-randomized, allocation concealed, participants and statistician blinded), 35 EFT vs 35 sham tapping vs 35 no-treatment control; four weekly individual 30-45 min sessions delivered by EFT Master-certified researchers (NCT06158672) |
| Comparison group | Sham tapping on non-acupoint locations (identical setup phrases, affirmations, breathing and session structure) plus a no-treatment control arm |
| Effect size | Cohen's d = 1.01 — on menopausal symptoms (MRS total, primary outcome), EFT vs sham tapping at posttest: d = 1.01 (EFT 10.14+/-5.96 vs sham 16.80+/-7.21, Tukey p=0.001), computed from author-reported posttest means/SDs; the sham comparison is used as the headline because it is the most conservative arm (EFT vs no-treatment control d = 1.29). Baseline equivalence confirmed (all pretest p>0.05). Secondary between-group posttest effects: Meno-D depression EFT vs sham d = 0.87 (sham within-group change non-significant, p=0.570), vs control d = 1.37; Meno-D sleep subscale EFT vs sham d = 1.30; MRS psychological subscale EFT vs sham d = 1.16. MSQLS total EFT vs sham d = 0.31, NOT significant - both tapping arms improved quality of life vs control. Sham vs control on MRS: d = 0.14, p=1.000. Null domains: vasomotor (hot flashes) and sexual scores did not change in any arm. |
| Outcome measures | Menopause Rating Scale (MRS, primary), Menopause-Specific Quality of Life Scale (MSQLS; higher = worse), Perimenopausal Depression Scale (Meno-D), Subjective Units of Experience (SUE) |
| Journal | Menopause |
| Year | 2026 |
| Country | Turkiye |
| Language | English |
| Method | EFT / Tapping |
| Publication type | Study / trial |
| Verification | ✓ Confirmed against the primary source |
Karatas Okyay, E., Guven Santur, S., Ozsahin, Z., & Karakayali Ay, C. (2026). The effect of emotional freedom techniques on menopausal symptoms, quality of life, and depression level: a randomized sham-controlled trial. Menopause. https://doi.org/10.1097/GME.0000000000002713
This record is part of the Tapping Evidence Base — an openly-sourced, fully-referenced directory of the research on EFT/Tapping. Explore more studies on Other Physical Conditions · Depression
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